Vaping Safety, Smoking, Dangers, Pros, Cons, Debate, E cigarettes, & Tobacco Britannica Electronic Nicotine Delivery Systems (ENDS), including e cigarettes and vapes, are often perceived as a safer alternative to traditional tobacco. But is the evidence really supporting this belief? A recent umbrella review published CDC Advises Public Not to Use E Cigarettes Primary health effects from smoking. Figure 1 used with permission from Download Scientific Diagram