Peripherally Inserted Central CatheterPICC Giving Medications and Heparin Flush CHOC Children's Health Hub Text Discharge Instructions: Changing the Dressing on Your Midline Catheter PICC line redness and soreness after dressing change? Central Line Dressing Change, , Central lines are at a high risk of serious infection. Proper central line care is a key to preventing these central line associated bloodstream infections called