Toxicity of Glutathione Binding Metals: A Review of Targets and Mechanisms Mycotoxins are toxic. But they are only one of many stressors affecting the extracellular matrix. Ochratoxin, aflatoxins, and trichothecenes increase oxidative stress, deplete glutathione, disrupt mitochondria, and activate inflammatory signaling. That Mycotoxin induced depletion of intracellular glutathione and altered cytokine production in the human alveolar epithelial cell line A549 ScienceDirect Can L Glutathione Support Energy and Detoxification in Long COVID and ME CFS? RTHM