Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which Frontiers Paracetamol Induced Glutathione Consumption: Is There a Link With Severe COVID 19 Illness? The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model Theoretical Biology and Medical Modelling Springer Nature Link