Glutathione and Side Effects: What You Need to Know for Better Health Performance Lab Taking glutathione but seeing no change? its frustrating. , Heres why it might not be working for you:, Your Gut May Be the Issue, If your gut isnt absorbing nutrients properly, glutathione cant Will IV glutathione work for everyone? With almost 10 years of experience, my answer is no. The results of IV glutathione vary depending on 1) what outcome we are using it for ( what to avoid when taking glutathione Patchmd