Everyone says NAC can make glutathione. Wrong. Evidence against this is staring right at you. As you can see here, my wife's GCLC gene is genetically slower. Thus, she cannot convert Cysteine Toxicity of Glutathione Binding Metals: A Review of Targets and Mechanisms Metabolomic Profiling Reveals Key Metabolic Alterations in MCF7 Tamoxifen Resistant Cells Following EPAS1 Inhibition ScienceDirect Oxidative stress contributes to the tamoxifen induced killing of breast cancer cells: implications for tamoxifen therapy and resistance Scientific Reports