B12 Injections for Energy: Benefits and How It Works AZ IV Medics Cyanocobalamin vs Hydroxocobalamin (Vitamin B12 forms) Key Clinical Differences Hydroxocobalamin is preferred in: Pernicious anemia Severe vitamin B12 deficiency Neurological symptoms (subacute combined degeneration, neuropathy) Cyanocobalamin is Vitamin B12 (cobalamin) and folate (vitamin B9) are vitamins that serve important functions in the human body. Folate is needed for development and growth of cells (including red blood cells) and synthesis How Long Does Vitamin B12 Take to Work? Timeline & Signs Performance Lab