Illustrated Glossary of Organic Chemistry Hydrophobic effect Have you ever wondered if the brain could heal itself? , The peptide Dihexa is making waves in the medical fieldand its currently being studied by the Michael J. Fox Foundation for its potential Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Small molecule activation of the neurotrophin hepatocyte growth factor to treat Alzheimer disease