How Much Nicotine is in a Vape? Compared to Cigarette Vaping vs. Smoking: What's the Nicotine Equivalent? Curious about how vaping compares to smoking? Let's break it down! Disposable Vapes: A typical disposable vape with around 600 puffs can Vaping in the UK: How Many Puffs? The nicotine content of many disposable vapes is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. #NoSmokingMonth Public Health Agency