Development of a novel senolytic by precise disruption of FOXO4 p53 complex eBioMedicine Most people learn about senescent cells from a podcast. I learned about them the hard way after pushing my body through the Grand Goals campaign and realizing that physical achievement doesn't mean Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology
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foxo4-dri senolytic human trial Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis