Vape to Cigarette Calculator: How Many Cigarettes Is Your Vape? Vaping vs. Smoking: What's the Nicotine Equivalent? Curious about how vaping compares to smoking? Let's break it down! Disposable Vapes: A typical disposable vape with around 600 puffs can Discover How Many Cigarettes in a Vape? Find Out Here! The nicotine in 1 vape can equal 50 cigarettes. Depending on the size of the vape and nicotine strength, it can be much higher. Nicotine can harm the developing brain, affecting